Analysis of Professor Wei Lianbo′s clinical medication rule in the treatment of chronic renal failure based on data mining
HU Fen1 HU Juan2▲ YANG Yanqun3 WANG Ziwei3 WEI Lianbo3
1. School of Pharmacy, Fujian University of Traditional Chinese Medicine
2. Institute Office, the Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine
3. Department of Traditional Chinese Medicine, Shenzhen Hospital of Southern Medical University
Abstract：Objective To explore the clinical medication rule of Professor Wei Lianbo in the treatment of chronic renal failure. Methods Based on the software of Traditional Chinese Medicine Inheritance Support System V2.5, the database was constructed, and the data mining method of software integration was used to analyze the syndrome, drug frequency and prescription rules of prescriptions. Results A total of 396 prescriptions met the inclusion criteria, involving 125 traditional Chinese medicines. The four qi of medicine were mainly warm, cold and mild heat. The five flavors of the medicine were mainly bitter, sweet, pungent and sour. The main meridian tropism of drugs were spleen, stomach, liver,lung and kidney. The syndrome was based on deficiency of spleen and kidney and marked by dampness and turbid toxin stasis. Salvia miltiorrhiza, Atractylodes macrocephala, rhubarb, Ligusticum chuanxiong, Pinellia ternata, Amomum villosum, Codonopsis pilosula, tangerine peel, Coptis chinensis, dried ginger, Achyranthes bidentata and Eucommia ulmoides were the core drug groups, which were mainly used to strengthen spleen and stomach, promote blood circulation and remove blood stasis, and nourish liver and kidney. Conclusion Professor Wei Lianbo′s treatment of chronic renal failure follows the principle of strengthening the body and removing pathogenic factors, treating both the symptoms and the root causes. He uses warm, cold and calm heat in his medication, and mostly uses invigorating the spleen and promoting blood circulation, tonifying the liver and kidney. The compatibility of each medicine plays the role of tonifying the spleen and kidney, clearing away dampness,heat and resolving turbidity.
胡芬；胡娟；羊燕群；王子威；魏连波. 基于数据挖掘的魏连波教授治疗慢性肾衰的临床用药规律分析[J]. 中国当代医药, 2022, 29(6): 98-102.
HU Fen；HU Juan；YANG Yanqun； WANG Ziwei；WEI Lianbo. Analysis of Professor Wei Lianbo′s clinical medication rule in the treatment of chronic renal failure based on data mining. 中国当代医药, 2022, 29(6): 98-102.
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