Abstract：Objective To investigate the repeatability and correctness of digital reading in clinical pathological diagnosis.Methods A total of 300 consecutive cases in Pathology Department of Chengdu First People′s Hospital diagnosed in September 2015 were chosen as research objects and all the slices were applied with digital scanning by whole slide images (WSI).The author reviewed slices again and made the first digital diagnosis, the second microscopic diagnosis, the second digital diagnosis separately in November 2015, January 2016 and March 2016.The four diagnosis results at different times and in different ways were compared, and the repeatability and correctness of digital reading in clinical pathological diagnosis was analyzed.Results Just as microscopic diagnosis, digital diagnosis had high repeatability and correctness in the nature and types of lesions.Compared with the coincidence rate of the first digital diagnosis and microscopic diagnosis, the coincidence rate of the second digital diagnosis and microscopic diagnosis was significantly higher.Whether it was microscopic or digital reading, the correctness of re-diagnosis of difficult cases was higher than that of initial diagnosis.Conclusion Digital reading has high repeatability and correctness in clinical pathological diagnosis.With the gradual adaptation of pathologists to digital reading, digital diagnosis will be more and more close to, or even beyond microscopic diagnosis in the repeatability and correctness.
唐仲平; 崔权哲; 包骥; 蔡玮; 赵春. 数字化阅片在病理诊断中的可重复性和正确率研究[J]. 中国当代医药, 2020, 27(3): 28-31.
TANG Zhong-ping; CUI Quan-zhe; BAO Ji; CAI Wei; ZHAO Chun. Study on repeatability and correctness of digital reading in pathological diagnosis. 中国当代医药, 2020, 27(3): 28-31.
Fung KM，Hassell LA，Talbert ML，et al.Whole slide images and digital media in pathology education，testing，and practice：the Oklahoma experience[J].Anal Cell Pathol，2012，35（1）：37-40.
Camparo P，Egevad L，Algaba F，et al.Utility of whole slide imaging and virtual microscopy in prostate pathology[J].APMIS，2012，120（4）：298-304.
[4]
Retamero JA，Aneiros-Fernandez J，Del Moral RG.Complete digital pathology for routine histopathology diagnosis in a multicenter hospital network[J].Arch Pathol Lab Med，2019.[Epub ahead of print].
[5]
Williams BJ，Knowles C，Treanor D.Maintaining quality diagnosis with digital pathology：A practical guide to ISO15189 accreditation[J].J Clin Pathol，2019.[Epub ahead of print].
[6]
Hanna MG，Pantanowitz L.Feasibility of using the omnyx digital pathology system for cytology practice[J].J Am Soc Cytopathol，2019，8（4）：182-189.
[7]
Hanna MG，Reuter VE，Samboy J，et al.Implementation of digital pathology offers clinical and operational increase in efficiency and cost savings[J].Arch Pathol Lab Med，2019，143（12）：1545-1555.
Paradis V，Quaglia A.Digital pathology，what is the future？[J].J Hepatol，2019，70（5）：1016-1018.
[13]
Tizhoosh HR，Pantanowitz L.Artificial intelligence and digital pathology：challenges and opportunities[J].J Pathol Inform，2018，9：38.
[14]
Higgins C.Applications and challenges of digital pathology and whole slide imaging[J].Biotech Histochem，2015，90（5）：341-347.
[15]
Wilbur DC，Madi K，Colvin RB，et al.Whole-slide imaging digital pathology as a platform for teleconsultation：a pilot study using paired subspecialist correlations[J].Arch Pathol Lab Med，2009，133（12）：1949-1953.
Colling R，Pitman H，Oien K，et al.Artificial intelligence in digital pathology：a roadmap to routine use in clinical practice[J].J Pathol，2019，249（2）：143-150.
[20]
Niazi MKK，Parwani AV，Gurcan MN.Digital pathology and artificial intelligence[J].Lancet Oncol，2019，20（5）：e253-e261.
[21]
Aeffner F，Zarella MD，Buchbinder N，et al.Introduction to digital image analysis in whole-slide imaging：A white paper from the digital pathology association[J].J Pathol Inform，2019，10：9.
京公网安备 11010502046607号