Abstract：Objective To investigate the clinical effect of Drotaverine combined with Tolterodine in the treatment of bladder spasm after transurethral resection of prostate.Methods Sixty patients with bladder spasm after transurethral resection of the prostate who were treated in Jiangxi Yingtan People′s Hospital Railway Branch from December 2016 to August 2018 were randomly selected as study objects and randomly divided into the treatment group （n=30）and the control group （n=30）.The control group was treated with Tolterodine，and the treatment group was treated with Drotaverine combined with Tolterodine.The number and duration time of bladder spasm after treatment were compared between the two groups.The overactive bladder symptom score （OABSS），bladder conditional awareness scale （PPBC）score，visual analogue scale （VAS）score，and quality of life （QOL）before and after treatment were compared between the two groups.Results There were no significant differences in the number and duration time of bladder spasm between the two groups at 24 h after treatment （P＞0.05）.The number of bladder spasm at 48 and 72 h after treatment in the two groups was fewer than that at 24 h after treatment，the duration time was shorter than that at 24 h after treatment，and the differences were statistically significant （P＜0.05）.The number of bladder spasm at 48 and 72 h after treatment in the treatment group was fewer than that in the control group，the duration time was shorter than that in the control group，and the differences were statistically significant （P＜0.05）.There were no significant differences in the scores of OABSS，PPBC and VAS between the two groups before treatment （P＞0.05）.The scores of OABSS，PPBC and VAS after treatment in the two groups were lower than those before treatment，and the differences were statistically sig-nificant（P＜0.05）.The scores of OABSS，PPBC and VAS after treatment in the treatment group were lower than those in the control group，and the differences were statistically significant （P＜0.05）.There was no significant difference in the score of QOL between the two groups before treatment （P＞0.05）.The scores of QOL after treatment in the two groups were higher than those before treatment，and the differences were statistically significant（P＜0.05）.The score of QOL after treatment in the treatment group was higher than that in the control group，and the difference was statistically significant（P＜0.05）.Conclusion Drotaverine combined with Tolterodine in the treatment of bladder spasm after transurethral resection of prostate has a satisfactory effect and high clinical value.
洪波;洪燕;庄娟. 屈他维林联合托特罗定治疗经尿道前列腺电切术后膀胱痉挛的临床效果[J]. 中国当代医药, 2019, 26(4): 114-117.
HONG Bo1HONG Yan2ZHUANG Juan3. Clinical effect of Drotaverine combined with Tolterodine in the treatment of bladder spasm after transurethral resection of prostate. 中国当代医药, 2019, 26(4): 114-117.
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