Effect of Shenqi Yiliu Formula combined with radiotherapy on immune function and prognosis of patients with middle and advanced cervical cancer
HUANG Chunlan1 HONG Huiqin2 SUN Yingfang3 ZENG Junlin4 YUAN Li1 ZOU Chengxiu1 LI Meili1
1. Department of Radiotherapy, Ganzhou Cancer Hospital, Jiangxi Province, Ganzhou 341000, China;
2. Department of Emergency, the First Affiliated Hospital of Gannan Medical College, Jiangxi Province, Ganzhou 341000, China;
3. Department of Nursing, Hospital of Gannan Normal University, Jiangxi Province, Ganzhou 341000, China;
4. Fuzhou Medical College, Nanchang University, Jiangxi Province, Fuzhou 344000, China
Abstract：Objective To explore the effect of Shenqi Yiliu Formula combined with radiotherapy on immune function and prognosis of patients with middle and advanced cervical cancer. Methods A total of 84 patients with advanced cervical cancer treated in Ganzhou Cancer Hospital from April 2015 to October 2018 were selected as the research subjects. According to random number table method, they were divided into control group (42 cases) and observation group (42 cases). The control group was treated with radiotherapy, and the observation group was treated with Shenqi Yiliu Formula combined with radiotherapy. The disease control rate, objective remission rate, immune function and prognosis were compared between the two groups. Results The objective remission rate of the observation group was 71.43%, higher than 47.62% of the control group, and the disease control rate of the observation group was 90.48%, higher than 69.05% of the control group, the differences were statistically significant (P<0.05). After treatment, CD3+, CD4+ and natural killer (NK) cells in the observation group were higher than those in the control group, the differences were statistically significant (P<0.05). The 3-year survival rate of the observation group was higher than that of the control group, and the overall incidence of tumor metastasis was lower than that of the control group, the differences were statistically significant (P<0.05). Conclusion Shenqi Yiliu Formula combined with radiotherapy has reliable efficacy in the treatment of patients with middle and advanced cervical cancer, which can improve immune function, reduce the total incidence of tumor metastasis and improve the 3-year survival rate.
黄春兰； 洪慧勤； 孙颖芳； 曾俊琳； 袁丽； 邹称秀； 李美丽. 参芪抑瘤方联合放疗对中晚期宫颈癌患者免疫功能及预后的影响[J]. 中国当代医药, 2022, 29(20): 88-91.
HUANG Chunlan； HONG Huiqin； SUN Yingfang； ZENG Junlin； YUAN Li； ZOU Chengxiu； LI Meili. Effect of Shenqi Yiliu Formula combined with radiotherapy on immune function and prognosis of patients with middle and advanced cervical cancer. 中国当代医药, 2022, 29(20): 88-91.
Liu C，Xiao C，Chen J，et al.Risk factor analysis for predicting cervical lymph node metastasis in papillary thyroid carcinoma：a study of 966 patients[J]. BMC Cancer，2019，19（1）：622.
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