Abstract：Objective To study the clinical effect of intensive insulin therapy in the treatment of diabetes mellitus complicated with acute cerebral infarction. Methods A total of 80 patients with diabetes complicated with acute cerebral infarction in the First Hospital of Nanping City, Fujian Province from January 2019 to January 2021 were selected as the research subjects and divided into an observation group and a control group by the random number table method,with 40 patients in each group. Patients in the control group received conventional treatment, while patients in the observation group received intensive insulin therapy. Blood glucose level, insulin function indicators and neurological deficit were compared between the two groups. Results After treatment, the levels of fasting blood glucose, 2-hour postprandial blood glucose and glycosylated hemoglobin in the observation group were lower than those in the control group, with statistically significant differences (P<0.05). After treatment, fasting insulin and insulin resistance levels in the observation group were lower than those in the control group, with statistically significant differences (P<0.05). The insulin β cells functional level in observation group was higher than that in the control group after treatment, and the difference was statistically significant (P<0.05). After treatment, the score of National Institutes of Health stroke scale in the observation group was lower than that in the control group, the difference was statistically significant (P<0.05).Conclusion Intensive insulin therapy for patients with diabetes complicated with acute cerebral infarction can not only stabilize the blood glucose level of patients, control their insulin resistance, but also improve neurological deficit of patients to a certain extent, with significant therapeutic effect.
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